BDNF Blocks Caspase-3 Activation in Neonatal Hypoxia–Ischemia

Hypoxic–ischemic (H-I) injury to the brain in the perinatal period often leads to significant long-term neurological deficits. In a model of neonatal H-I injury in postnatal day 7 rats, our previous data have shown that cell death with features of apoptosis is prominent between 6 and 24 h after H-I...

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Bibliographic Details
Main Authors: Byung Hee Han, Anselm D'Costa, Stephen A. Back, Maia Parsadanian, Shilen Patel, Aarti R. Shah, Jeffrey M. Gidday, Anu Srinivasan, Mohanish Deshmukh, David M. Holtzman
Format: Article
Language:English
Published: Elsevier 2000-02-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996199902759