Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer’s disease

Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer’s disease

Abstract Background The human brain is complex and interconnected structurally. Brain connectome change is associated with Alzheimer’s disease (AD) and other neurodegenerative diseases. Genetics and genomics studies have identified molecular changes in AD; however, the results are often limited to i...

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Bibliographic Details
Main Authors: Young Jae Woo, Panos Roussos, Vahram Haroutunian, Pavel Katsel, Samuel Gandy, Eric E. Schadt, Jun Zhu, Alzheimer Disease Neuroimaging Initiative (ADNI)
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Medicine
Subjects:
Alzheimer’s disease
Diffusion tensor imaging
Transcriptome
Post-mortem brain
Imaging transcriptomics
Toll-like receptor signaling
Online Access:https://doi.org/10.1186/s12916-019-1488-1

Internet

https://doi.org/10.1186/s12916-019-1488-1

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