Targeting the Hepatocyte Growth Factor and c-Met Signaling Axis in Bone Metastases

Targeting the Hepatocyte Growth Factor and c-Met Signaling Axis in Bone Metastases

Bone metastasis is the terminal stage disease of prostate, breast, renal, and lung cancers, and currently no therapeutic approach effectively cures or prevents its progression to bone metastasis. One of the hurdles to the development of new drugs for bone metastasis is the complexity and heterogenei...

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Bibliographic Details
Main Authors: Young Mi Whang, Seung Pil Jung, Meyoung-Kon Kim, In Ho Chang, Serk In Park
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
bone
metastasis
microenvironment
osteoblasts
osteoclasts
bone marrow
c-Met and hepatocyte growth factor
Online Access:http://www.mdpi.com/1422-0067/20/2/384

Internet

http://www.mdpi.com/1422-0067/20/2/384

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