Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier.

The polymeric mucin component of the intestinal mucus barrier changes during nematode infection to provide not only physical protection but also to directly affect pathogenic nematodes and aid expulsion. Despite this, the direct interaction of the nematodes with the mucins and the mucus barrier has...

Full description

Bibliographic Details
Main Authors: Sumaira Z Hasnain, Michael A McGuckin, Richard K Grencis, David J Thornton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3469553?pdf=render