Deuteration enhances the anti-tumor effects and relative anti-inflammatory effects via affecting proliferation and apoptosis

Deuteration enhances the anti-tumor effects and relative anti-inflammatory effects via affecting proliferation and apoptosis

Apigenin (AP) is a plant flavonoid with potential biomedical applications. To enhance the anti-tumour effect, AP was deuterated via hydrogen–deuterium exchange under hydrothermal conditions. The anti-tumor effects of deuterated AP (D-AP) were then tested on HCT116 cells and on a murine model of turp...

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Bibliographic Details
Main Authors: Ao Li, Xiaojiao Wang, Danni Li, Xiaohong Li, Rou Li, Xuejuan Yang, Xiao Li
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Heliyon
Subjects:
Apigenin
Deuteration
Apoptosis
Cell proliferation
Anti-inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021004965

Internet

http://www.sciencedirect.com/science/article/pii/S2405844021004965

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