The therapeutic potential of induced hepatocyte-like cells generated by direct reprogramming on hepatic fibrosis

The therapeutic potential of induced hepatocyte-like cells generated by direct reprogramming on hepatic fibrosis

Abstract Background Until now, there is no effective anti-fibrotic therapy available for liver cirrhosis. Stem cell therapies have been studied for the treatment of hepatic fibrosis. However, the use of embryonic stem cells or induced pluripotent stem cells (iPSC) has limitations such as ethical con...

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Bibliographic Details
Main Authors: Suhyun Park, Seon In Hwang, Jonghun Kim, Seoyeon Hwang, Sohee Kang, Sera Yang, Jonghwa Kim, Wonseok Kang, Kyun-Hwan Kim, Dong Wook Han, Yong-Han Paik
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Stem Cell Research & Therapy
Subjects:
Animal models
Disease modeling
CCl4
Stem cell transplantation
Hepatic fibrosis
Cell and tissue-based therapy
Online Access:http://link.springer.com/article/10.1186/s13287-018-1127-3

Internet

http://link.springer.com/article/10.1186/s13287-018-1127-3

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