High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival.

High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival.

Ca2+-activated K+ channels have been implicated in cancer cell growth, metastasis, and tumor angiogenesis. Here we hypothesized that high mRNA and protein expression of the intermediate-conductance Ca2+-activated K+ channel, KCa3.1, is a molecular marker of clear cell Renal Cell Carcinoma (ccRCC) an...

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Bibliographic Details
Main Authors: Maj Rabjerg, Aida Oliván-Viguera, Lars Koch Hansen, Line Jensen, Linda Sevelsted-Møller, Steen Walter, Boye L Jensen, Niels Marcussen, Ralf Köhler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4388734?pdf=render

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http://europepmc.org/articles/PMC4388734?pdf=render

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