Acute liver injury induced by low dose dimethylnitrosamine alters mediators of hepatic vascular flow

Alterations in liver vascular tone play an important role in chronic liver disease. The hepatic stellate cell (HSC) and mediators such as nitric oxide (NO) and hydrogen sulfide (H2S) have been implicated in regulation of vascular tone and intra-hepatic pressure. Though these have been studied in chr...

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Main Authors: G. Jayakumar Amirtharaj, Kavitha R. Thangaraj, Archana Kini, Raghupathy V., Ashish Goel, Eapen C.E., Aparna Venkatraman, Anna B. Pulimood, Balasubramanian K.A., Anup Ramachandran
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014000821