Irisin Induces Angiogenesis in Human Umbilical Vein Endothelial Cells In Vitro and in Zebrafish Embryos In Vivo via Activation of the ERK Signaling Pathway.

Irisin Induces Angiogenesis in Human Umbilical Vein Endothelial Cells In Vitro and in Zebrafish Embryos In Vivo via Activation of the ERK Signaling Pathway.

As a link between exercise and metabolism, irisin is assumed to be involved in increased total body energy expenditure, reduced body weight, and increased insulin sensitivity. Although our recent evidence supported the contribution of irisin to vascular endothelial cell (ECs) proliferation and apopt...

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Main Authors: Fei Wu, Haibo Song, Yuan Zhang, Yuzhu Zhang, Qian Mu, Miao Jiang, Fang Wang, Wen Zhang, Liang Li, Huanjie Li, Yunshan Wang, Mingxiang Zhang, Shiwu Li, Lijun Yang, Yan Meng, Dongqi Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4524626?pdf=render

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http://europepmc.org/articles/PMC4524626?pdf=render

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