NAD⁺-carrying mesoporous silica nanoparticles can prevent oxidative stress-induced energy failures of both rodent astrocytes and PC12 cells.
AIM: To test the hypothesis that NAD(+)-carrying mesoporous silica nanoparticles (M-MSNs@NAD+) can effectively deliver NAD(+) into cells to produce cytoprotective effects. METHODS & MATERIALS: NAD(+) was incorporated into M-MSNs. Primary rat astrocyte cultures and PC12 cells were treated with H₂...
Main Authors: | Heyu Chen, Yao Wang, Jixi Zhang, Yingxin Ma, Caixia Wang, Ying Zhou, Hongchen Gu, Weihai Ying |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3767595?pdf=render |
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