Purge Haplotigs: allelic contig reassignment for third-gen diploid genome assemblies

Purge Haplotigs: allelic contig reassignment for third-gen diploid genome assemblies

Abstract Background Recent developments in third-gen long read sequencing and diploid-aware assemblers have resulted in the rapid release of numerous reference-quality assemblies for diploid genomes. However, assembly of highly heterozygous genomes is still problematic when regional heterogeneity is...

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Bibliographic Details
Main Authors: Michael J. Roach, Simon A. Schmidt, Anthony R. Borneman
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Bioinformatics
Subjects:
Synteny reduction
Redundant contigs
Polymorphic genome
Online Access:http://link.springer.com/article/10.1186/s12859-018-2485-7

Internet

http://link.springer.com/article/10.1186/s12859-018-2485-7

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