Purge Haplotigs: allelic contig reassignment for third-gen diploid genome assemblies
Abstract Background Recent developments in third-gen long read sequencing and diploid-aware assemblers have resulted in the rapid release of numerous reference-quality assemblies for diploid genomes. However, assembly of highly heterozygous genomes is still problematic when regional heterogeneity is...
Main Authors: | Michael J. Roach, Simon A. Schmidt, Anthony R. Borneman |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2485-7 |
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