Altered Expression of Genes in Signaling Pathways Regulating Proliferation of Hematopoietic Stem and Progenitor Cells in Mice with Subchronic Benzene Exposure

Altered Expression of Genes in Signaling Pathways Regulating Proliferation of Hematopoietic Stem and Progenitor Cells in Mice with Subchronic Benzene Exposure

Leukemias and hematopoietic disorders induced by benzene may arise from the toxicity of benzene to hematopoietic stem or progenitor cells (HS/PCs). Since there is a latency period between initial benzene exposure and the development of leukemia, subsequent impact of benzene on HS/PCs are crucial for...

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Bibliographic Details
Main Authors: Rongli Sun, Juan Zhang, Mengzhen Xiong, Haiyan Wei, Kehong Tan, Lihong Yin, Yuepu Pu
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:International Journal of Environmental Research and Public Health
Subjects:
benzene
post-exposure toxicity
hematopoietic stem cell
Wnt
Notch
Hedghog
Online Access:http://www.mdpi.com/1660-4601/12/8/9298

Internet

http://www.mdpi.com/1660-4601/12/8/9298

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