Potential Role of CXCR4 Targeting in the Context of Radiotherapy and Immunotherapy of Cancer

Cancer immunotherapy has been established as standard of care in different tumor entities. After the first reports on synergistic effects with radiotherapy and the induction of abscopal effects—tumor shrinkage outside the irradiated volume attributed to immunological effects of radiotherapy—several...

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Bibliographic Details
Main Authors: Franziska Eckert, Karin Schilbach, Lukas Klumpp, Lilia Bardoscia, Efe Cumhur Sezgin, Matthias Schwab, Daniel Zips, Stephan M. Huber
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03018/full