Putative zinc finger protein binding sites are over-represented in the boundaries of methylation-resistant CpG islands in the human genome.
<h4>Background</h4>Majority of CpG dinucleotides in mammalian genomes tend to undergo DNA methylation, but most CpG islands are resistant to such epigenetic modification. Understanding about mechanisms that may lead to the methylation resistance of CpG islands is still very poor.<h4&g...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-11-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0001184 |