Building in-house PBPK modelling tools for oral drug administration from literature information

The interest in using physiologically-based pharmacokinetic (PBPK) models as a support to the drug development decision making process has rapidly increased in the last years. These kind of models are examples of the “bottom up” modelling strategy, which progressively integrates into a mechanistic f...

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Bibliographic Details
Main Authors: Silvia Grandoni, Nicola Cesari, Giandomenico Brogin, Paola Puccini, Paolo Magni
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2019-02-01
Series:ADMET and DMPK
Subjects:
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/638