HMGB1, NLRP3, IL-6 and ACE2 levels are elevated in COVID-19 with headache: a window to the infection-related headache mechanism

HMGB1, NLRP3, IL-6 and ACE2 levels are elevated in COVID-19 with headache: a window to the infection-related headache mechanism

Abstract Background and aim Pathogenesis of COVID-19 -related headache is unknown, though the induction of the trigeminal neurons through inflammation is proposed. We aimed to investigate key systemic circulating inflammatory molecules and their clinical relations in COVID-19 patients with headache....

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Bibliographic Details
Main Authors: Hayrunnisa Bolay, Ömer Karadas, Bilgin Oztürk, Riza Sonkaya, Bahar Tasdelen, Tuba D. S. Bulut, Özlem Gülbahar, Aynur Özge, Betül Baykan
Format: Article
Language:English
Published: BMC 2021-08-01
Series:The Journal of Headache and Pain
Subjects:
COVID-19
Headache
Inflammation
NLRP3
HMGB1
ACE2
Online Access:https://doi.org/10.1186/s10194-021-01306-7

Internet

https://doi.org/10.1186/s10194-021-01306-7

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