Comparison of Major and Minor Viral SNPs Identified through Single Template Sequencing and Pyrosequencing in Acute HIV-1 Infection.

Comparison of Major and Minor Viral SNPs Identified through Single Template Sequencing and Pyrosequencing in Acute HIV-1 Infection.

Massively parallel sequencing (MPS) technologies, such as 454-pyrosequencing, allow for the identification of variants in sequence populations at lower levels than consensus sequencing and most single-template Sanger sequencing experiments. We sought to determine if the greater depth of population s...

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Bibliographic Details
Main Authors: Shyamala Iyer, Eleanor Casey, Heather Bouzek, Moon Kim, Wenjie Deng, Brendan B Larsen, Hong Zhao, Roger E Bumgarner, Morgane Rolland, James I Mullins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4552882?pdf=render

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http://europepmc.org/articles/PMC4552882?pdf=render

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