Pharmacogenetic Testing for Prevention of Severe Cutaneous Adverse Drug Reactions

Pharmacogenetic Testing for Prevention of Severe Cutaneous Adverse Drug Reactions

Severe cutaneous adverse reactions (SCAR), such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug rash with eosinophilia and systemic symptoms (DRESS), are idiosyncratic and unpredictable drug-hypersensitivity reactions with a high-mortality rate ranging from 10% to over...

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Bibliographic Details
Main Authors: Chih-Jung Chang, Chun-Bing Chen, Shuen-Iu Hung, Chao Ji, Wen-Hung Chung
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
drug hypersensitivity
pharmacogenetics
severe cutaneous adverse reactions
human-leukocyte antigen
T cell receptor
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00969/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00969/full

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