Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro.

Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro.

Haemophilus ducreyi resists the cytotoxic effects of human antimicrobial peptides (APs), including α-defensins, β-defensins, and the cathelicidin LL-37. Resistance to LL-37, mediated by the sensitive to antimicrobial peptide (Sap) transporter, is required for H. ducreyi virulence in humans. Cationic...

Full description

Bibliographic Details
Main Authors: Michael P Trombley, Deborah M B Post, Sherri D Rinker, Lorri M Reinders, Kate R Fortney, Beth W Zwickl, Diane M Janowicz, Fitsum M Baye, Barry P Katz, Stanley M Spinola, Margaret E Bauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4406763?pdf=render

Internet

http://europepmc.org/articles/PMC4406763?pdf=render

Similar Items