Investigation of Bemethyl Biotransformation Pathways by Combination of LC–MS/HRMS and In Silico Methods

Investigation of Bemethyl Biotransformation Pathways by Combination of LC–MS/HRMS and In Silico Methods

Bemethyl is an actoprotector, an antihypoxant, and a moderate psychostimulant. Even though the therapeutic effectiveness of bemethyl is well documented, there is a gap in knowledge regarding its metabolic products and their quantitative and qualitative characteristics. Since 2018, bemethyl is includ...

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Bibliographic Details
Main Authors: Daria A. Belinskaia, Elena I. Savelieva, Georgy V. Karakashev, Olga I. Orlova, Mikhail A. Leninskii, Nataliia S. Khlebnikova, Natalia N. Shestakova, Alexandra R. Kiskina
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
bemethyl
2-(ethylthio)benzimidazole
actoprotector
doping
rat urine
metabolite
Online Access:https://www.mdpi.com/1422-0067/22/16/9021

Internet

https://www.mdpi.com/1422-0067/22/16/9021

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