Density of common complex ocular traits in the aging eye: analysis of secondary traits in genome-wide association studies.

Genetic association studies are identifying genetic risks for common complex ocular traits such as age-related macular degeneration (AMD). The subjects used for discovery of these loci have been largely from clinic-based, case-control studies. Typically, only the primary phenotype (e.g., AMD) being...

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Bibliographic Details
Main Authors: Albert O Edwards, Sung J Lee, Brooke L Fridley, Nirubol Tosakulwong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2424139?pdf=render