In vivo dissolution of poorly water-soluble drugs: Proof of concept based on fluorescence bioimaging

In vivo dissolution of poorly water-soluble drugs: Proof of concept based on fluorescence bioimaging

In vitro‒in vivo correlation (IVIVC) of solid dosage forms should be established basically between in vitro and in vivo dissolution of active pharmaceutical ingredients. Nevertheless, in vivo dissolution profiles have never been accurately portrayed. The current practice of IVIVC has to resort to in...

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Bibliographic Details
Main Authors: Yinqian Yang, Yongjiu Lv, Chengying Shen, Tingting Shi, Haisheng He, Jianping Qi, Xiaochun Dong, Weili Zhao, Yi Lu, Wei Wu
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
In vivo dissolution
Fenofibrate
Fluorescence
Aggregation-caused quenching
Bioimaging
IVIVC
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383520306717

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http://www.sciencedirect.com/science/article/pii/S2211383520306717

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