HOXA5 Expression Is Elevated in Breast Cancer and Is Transcriptionally Regulated by Estradiol

HOXA5 Expression Is Elevated in Breast Cancer and Is Transcriptionally Regulated by Estradiol

HOXA5 is a homeobox-containing gene associated with the development of the lung, gastrointestinal tract, and vertebrae. Here, we investigate potential roles and the gene regulatory mechanism in HOXA5 in breast cancer cells. Our studies demonstrate that HOXA5 expression is elevated in breast cancer t...

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Bibliographic Details
Main Authors: Imran Hussain, Paromita Deb, Avisankar Chini, Monira Obaid, Arunoday Bhan, Khairul I. Ansari, Bibhu P. Mishra, Samara A. Bobzean, S. M. Nashir Udden, Prasanna G. Alluri, Hriday K. Das, Robert Matthew Brothers, Linda I. Perrotti, Subhrangsu S. Mandal
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Genetics
Subjects:
HOXA5
breast cancer
estradiol
gene expression
estrogen receptors
chromatin
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.592436/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.592436/full

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