Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines
<p>Abstract</p> <p>Background</p> <p>STAT3 [1] has been shown to be dysregulated in nearly every major cancer, including osteosarcoma (OS). Constitutive activation of STAT3, via aberrant phosphorylation, leads to proliferation, cell survival and resistance to apoptosis....
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-12-01
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| Series: | BMC Veterinary Research |
| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1746-6148/8/244 |