Jieduquyuziyin Prescription Suppresses Inflammatory Activity of MRL/lpr Mice and Their Bone Marrow-Derived Macrophages via Inhibiting Expression of IRAK1-NF-κB Signaling Pathway

Jieduquyuziyin Prescription Suppresses Inflammatory Activity of MRL/lpr Mice and Their Bone Marrow-Derived Macrophages via Inhibiting Expression of IRAK1-NF-κB Signaling Pathway

Jieduquyuziyin prescription (JP) has been used to treat systemic lupus erythematosus (SLE). Although the effectiveness of JP in the treatment of SLE has been clinically proven, the underlying mechanisms have yet to be completely understood. We observed the therapeutic actions of JP in MRL/lpr mice a...

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Bibliographic Details
Main Authors: Lina Ji, Xuemin Fan, Xiaoli Hou, Danqing Fu, Jie Bao, Aiwen Zhuang, Sixiang Chen, Yongsheng Fan, Rongqun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
Jieduquyuziyin prescription
MRL/lpr mice
bone marrow-derived macrophages
IRAK1-NF-κB signalling
systemic lupus erythematosus
inflammatory activity
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01049/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.01049/full

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