Essential role for a novel population of binucleated mammary epithelial cells in lactation

The main function of the mammary gland is to produce milk to sustain offspring. Here, the authors show that secretory alveolar cells in the lactating gland in several species are binucleated, which increases milk production, and that binucleation is regulated by Aurora kinase-A and Polo-like kinase-...

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Bibliographic Details
Main Authors: Anne C. Rios, Nai Yang Fu, Paul R. Jamieson, Bhupinder Pal, Lachlan Whitehead, Kevin R. Nicholas, Geoffrey J. Lindeman, Jane E. Visvader
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11400