CREG ameliorates the phenotypic switching of cardiac fibroblasts after myocardial infarction via modulation of CDC42

CREG ameliorates the phenotypic switching of cardiac fibroblasts after myocardial infarction via modulation of CDC42

Abstract Phenotype switching of cardiac fibroblasts into myofibroblasts plays important role in cardiac fibrosis following myocardial infarction (MI). Cellular repressor of E1A-stimulated genes (CREG) protects against vascular and cardiac remodeling induced by angiotensin-II. However, the effects an...

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Bibliographic Details
Main Authors: Dan Liu, Xiaoxiang Tian, Yanxia Liu, Haixu Song, Xiaoli Cheng, Xiaolin Zhang, Chenghui Yan, Yaling Han
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03623-w

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https://doi.org/10.1038/s41419-021-03623-w

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