Cirbp-PSD95 axis protects against hypobaric hypoxia-induced aberrant morphology of hippocampal dendritic spines and cognitive deficits

Cirbp-PSD95 axis protects against hypobaric hypoxia-induced aberrant morphology of hippocampal dendritic spines and cognitive deficits

Abstract Hypobaric hypoxia (HH) is a typical characteristic of high altitude environment and causes a spectrum of pathophysiological effects, including headaches, gliovascular dysfunction and cognitive retardation. Here, we sought to understand the mechanisms underlying cognitive deficits under HH e...

Full description

Bibliographic Details
Main Authors: Yang Zhou, Huanyu Lu, Ying Liu, Zaihua Zhao, Qian Zhang, Chong Xue, Yuankang Zou, Zipeng Cao, Wenjing Luo
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Molecular Brain
Subjects:
Hypobaric hypoxia
High altitude environment
Cognitive impairment
Dendritic spine morphology
Cold-inducible RNA-binding protein
PSD95
Online Access:https://doi.org/10.1186/s13041-021-00827-1

Internet

https://doi.org/10.1186/s13041-021-00827-1

Similar Items