Exosomes mediate LTB4 release during neutrophil chemotaxis.
Leukotriene B4 (LTB4) is secreted by chemotactic neutrophils, forming a secondary gradient that amplifies the reach of primary chemoattractants. This strategy increases the recruitment range for neutrophils and is important during inflammation. Here, we show that LTB4 and its synthesizing enzymes lo...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-07-01
|
Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3001271 |