Cell Proliferation is Strongly Associated with the Treatment Conditions of an ER Stress Inducer New Anti-Melanoma Drug in Melanoma Cell Lines

Cell Proliferation is Strongly Associated with the Treatment Conditions of an ER Stress Inducer New Anti-Melanoma Drug in Melanoma Cell Lines

HA15 is a new anti-melanoma drug that triggers endoplasmic reticulum (ER) stress and causes deleterious effects on melanoma cell viability due to autophagy and apoptosis, regardless of driver mutations or drug resistance. In this study, we investigated the effect of HA15 on the viability/proliferati...

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Bibliographic Details
Main Authors: István Szász, Viktória Koroknai, Vikas Patel, Tibor Hajdú, Tímea Kiss, Róza Ádány, Margit Balázs
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
HA15 anti-melanoma drug
ER stress
apoptosis
autophagy
resistant cell lines
RNA-Seq
Online Access:https://www.mdpi.com/2227-9059/9/2/96

Internet

https://www.mdpi.com/2227-9059/9/2/96

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