Novel effect of berberine on thermoregulation in mice model induced by hot and cold environmental stimulation.

The purpose of this study was to assess the effects of berberine (BBR) on thermoregulation in mice exposed to hot (40°C) and cold (4°C) environmental conditions. Four groups of mice were assembled with three different dosages of BBR (0.2, 0.4, and 0.8 mg/kg) and normal saline (control). In room temp...

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Bibliographic Details
Main Authors: Jing-Fei Jiang, Yu-Gang Wang, Jun Hu, Fan Lei, Michael M Kheir, Xin-Pei Wang, Yu-Shuang Chai, Zhi-Yi Yuan, Xi Lu, Dong-Ming Xing, Feng Du, Li-Jun Du
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3545878?pdf=render