Endocrine profile of the VCD-induced perimenopausal model rat.

During the transition to menopause, women experience a variety of physical and psychological symptoms that are directly or indirectly linked to changes in hormone secretion. Establishing animal models with intact ovaries is essential for understanding these interactions and finding new therapeutic t...

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Bibliographic Details
Main Authors: Ruither O G Carolino, Paulo T Barros, Bruna Kalil, Janete Anselmo-Franci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226874