Short- and long-term effects on reproductive parameters of female Wistar rats after exposure to rosuvastatin starting in pre-puberty

Statins are a class of drugs that act lowering lipid levels by inhibiting cholesterol biosynthesis. Additionally, statins can act by “pleiotropic effects”, related to the inhibition of synthesis of the other mevalonate pathway products. Rosuvastatin is a third-generation statin and has shown better...

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Bibliographic Details
Main Authors: Jorge W.F. Barros, Karolina S. Tonon, Cibele S. Borges, Patrícia V. Silva, Ana F.Q. Lozano, Tainá L. Pacheco, Janete A. Anselmo-Franci, Wilma G. Kempinas
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Current Research in Toxicology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X20300190