Mitochondrial DNA mutations associated with aminoglycoside induced ototoxicity

Aminoglycosides (AmAn) are widely used for their great efficiency against gram-negative bacterial infections. However, they can also induce ototoxic hearing loss, which has affected millions of people around the world. As previously reported, individuals bearing mitochondrial DNA mutations in the 12...

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Bibliographic Details
Main Authors: Zewen Gao, Ye Chen, Min-Xin Guan
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Journal of Otology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1672293016300885