The Role of Succinate in the Regulation of Intestinal Inflammation

Succinate is a metabolic intermediate of the tricarboxylic acid (TCA) cycle within host cells. Succinate is also produced in large amounts during bacterial fermentation of dietary fiber. Elevated succinate levels within the gut lumen have been reported in association with microbiome disturbances (dy...

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Bibliographic Details
Main Authors: Jessica Connors, Nick Dawe, Johan Van Limbergen
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/11/1/25