Redox-Responsive Nanophotosensitizer Composed of Chlorin e6-Conjugated Dextran for Photodynamic Treatment of Colon Cancer Cells

We synthesized dextran-chlorin e6 conjugates having disulfide linkage for specific targeting of colonic region and cancer cells. Reductive end group of dextran was treated with sodium borocyanohydride and conjugated with cystamine. Cystamine end group was conjugated with carboxylic acid of chlorin e...

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Bibliographic Details
Main Authors: Chong Woo Chu, Je Ho Ryu, Young-IL Jeong, Tae Won Kwak, Hye Lim Lee, Hyun Yul Kim, Gyung Mo Son, Hyung Wook Kim, Dae Hwan Kang
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2016/4075803