Mucoadhesive Budesonide Formulation for the Treatment of Eosinophilic Esophagitis

Mucoadhesive Budesonide Formulation for the Treatment of Eosinophilic Esophagitis

Eosinophilic esophagitis (EE) is a chronic immune/antigen-mediated esophageal inflammatory disease for which off-label topical corticosteroids (e.g., budesonide) are widely used in clinic. In general, thickening excipients are mixed with industrial products to improve the residence time of the drug...

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Bibliographic Details
Main Authors: Antonella Casiraghi, Chiara Grazia Gennari, Umberto Maria Musazzi, Marco Aldo Ortenzi, Susanna Bordignon, Paola Minghetti
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
eosinophilic esophagitis
budesonide
xanthan gum
guar gum
mucoadhesion
esophagus permeability
rheological characterization
pediatric medicine
compounded preparation
Online Access:https://www.mdpi.com/1999-4923/12/3/211

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https://www.mdpi.com/1999-4923/12/3/211

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