Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair

Sarcolemma lesions are sealed by a repair patch of lipids and proteins that prevents cell death and myopathy. Here the authors show that the "eat-me" signal phosphatidylserine is sorted from adjacent sarcolemma to the repair patch in a Dysferlin dependent process in zebrafish and human cel...

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Bibliographic Details
Main Authors: Volker Middel, Lu Zhou, Masanari Takamiya, Tanja Beil, Maryam Shahid, Urmas Roostalu, Clemens Grabher, Sepand Rastegar, Markus Reischl, Gerd Ulrich Nienhaus, Uwe Strähle
Format: Article
Language:English
Published: Nature Publishing Group 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12875