FGD5-AS1 Is a Hub lncRNA ceRNA in Hearts With Tetralogy of Fallot Which Regulates Congenital Heart Disease Genes Transcriptionally and Epigenetically

FGD5-AS1 Is a Hub lncRNA ceRNA in Hearts With Tetralogy of Fallot Which Regulates Congenital Heart Disease Genes Transcriptionally and Epigenetically

Heart development requires robust gene regulation, and the related disruption could lead to congenital heart disease (CHD). To gain insights into the regulation of gene expression in CHD, we obtained the expression profiles of long non-coding RNAs (lncRNAs) and messenger RNAs (mRNAs) in 22 heart tis...

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Bibliographic Details
Main Authors: Xingyu Zhang, Yunqian Gao, Xiaoping Zhang, Xiaoqing Zhang, Ying Xiang, Qihua Fu, Bo Wang, Zhuoming Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
congenital heart disease
gene expression
lncRNA
FGD5-AS1
tetralogy of Fallot
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.630634/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.630634/full

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