Synthesis of a Vpr-Binding Derivative for Use as a Novel HIV-1 Inhibitor.

Synthesis of a Vpr-Binding Derivative for Use as a Novel HIV-1 Inhibitor.

The emergence of multidrug-resistant viruses compromises the efficacy of anti-human immunodeficiency virus type 1 (HIV-1) therapy and limits treatment options. Therefore, new targets that can be used to develop novel antiviral agents need to be identified. We previously identified a potential parent...

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Bibliographic Details
Main Authors: Kyoji Hagiwara, Hideki Ishii, Tomoyuki Murakami, Shin-nosuke Takeshima, Nopporn Chutiwitoonchai, Eiichi N Kodama, Kumi Kawaji, Yasumitsu Kondoh, Kaori Honda, Hiroyuki Osada, Yasuko Tsunetsugu-Yokota, Masaaki Suzuki, Yoko Aida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4689350?pdf=render

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http://europepmc.org/articles/PMC4689350?pdf=render

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