Knockdown of Rab5a expression decreases cancer cell motility and invasion through integrin-mediated signaling pathway

<p>Abstract</p> <p>Background</p> <p>Rab GTPases function as modulators in intracellular transport. Rab5a, a member of the Rab subfamily of small GTPases, is an important regulator of vesicle traffic from the plasma membrane to early endosomes. Recent findings have repo...

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Bibliographic Details
Main Authors: Shi Shu-liang, Zheng Hong-xia, Chen Xiang-mei, Liu Shan-shan, Li Yu
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/18/1/58