Recommendations for Accurate Resolution of Gene and Isoform Allele-Specific Expression in RNA-Seq Data.

Recommendations for Accurate Resolution of Gene and Isoform Allele-Specific Expression in RNA-Seq Data.

Genetic variation modulates gene expression transcriptionally or post-transcriptionally, and can profoundly alter an individual's phenotype. Measuring allelic differential expression at heterozygous loci within an individual, a phenomenon called allele-specific expression (ASE), can assist in i...

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Bibliographic Details
Main Authors: David L A Wood, Katia Nones, Anita Steptoe, Angelika Christ, Ivon Harliwong, Felicity Newell, Timothy J C Bruxner, David Miller, Nicole Cloonan, Sean M Grimmond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0126911

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https://doi.org/10.1371/journal.pone.0126911

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