Environmental oxygen tension regulates the energy metabolism and self-renewal of human embryonic stem cells.

Environmental oxygen tension regulates the energy metabolism and self-renewal of human embryonic stem cells.

Energy metabolism is intrinsic to cell viability but surprisingly has been little studied in human embryonic stem cells (hESCs). The current study aims to investigate the effect of environmental O2 tension on carbohydrate utilisation of hESCs. Highly pluripotent hESCs cultured at 5% O2 consumed sign...

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Bibliographic Details
Main Authors: Catherine E Forristal, David R Christensen, Fay E Chinnery, Raffaella Petruzzelli, Kate L Parry, Tilman Sanchez-Elsner, Franchesca D Houghton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3645991?pdf=render

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http://europepmc.org/articles/PMC3645991?pdf=render

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