RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.

EHBP-1 (Ehbp1) is a conserved regulator of endocytic recycling, acting as an effector of small GTPases including RAB-10 (Rab10). Here we present evidence that EHBP-1 associates with tubular endosomal phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] enriched membranes through an N-terminal C2-like (...

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Bibliographic Details
Main Authors: Peixiang Wang, Hang Liu, Yu Wang, Ou Liu, Jing Zhang, Adenrele Gleason, Zhenrong Yang, Hui Wang, Anbing Shi, Barth D Grant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1006093