Efficient pairwise RNA structure prediction and alignment using sequence alignment constraints

<p>Abstract</p> <p>Background</p> <p>We are interested in the problem of predicting secondary structure for small sets of homologous RNAs, by incorporating limited comparative sequence information into an RNA folding model. The Sankoff algorithm for simultaneous RNA fol...

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Bibliographic Details
Main Authors: Dowell Robin D, Eddy Sean R
Format: Article
Language:English
Published: BMC 2006-09-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/7/400