Differentiation of Mouse Embryonic Stem Cells toward Functional Pancreatic β-Cell Surrogates through Epigenetic Regulation of by Nitric Oxide

Differentiation of Mouse Embryonic Stem Cells toward Functional Pancreatic β-Cell Surrogates through Epigenetic Regulation of by Nitric Oxide

Pancreatic and duodenal homeobox 1 (Pdx1) is a transcription factor that regulates the embryonic development of the pancreas and the differentiation toward β cells. Previously, we have shown that exposure of mouse embryonic stem cells (mESCs) to high concentrations of diethylenetriamine nitric oxide...

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Bibliographic Details
Main Authors: Carmen Salguero-Aranda, Rafael Tapia-Limonchi, Gladys Margot Cahuana, Ana Belen Hitos, Irene Diaz, Abdelkrim Hmadcha, Mario Fraga, Franz Martín, Bernat Soria, Juan Rigoberto Tejedo, Francisco Javier Bedoya
Format: Article
Language:English
Published: SAGE Publishing 2016-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368916X691178

Internet

https://doi.org/10.3727/096368916X691178

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