Serum-Free Suspension Culture of MDCK Cells for Production of Influenza H1N1 Vaccines.

Development of serum-free suspension cell culture processes is very important for influenza vaccine production. Previously, we developed a MDCK suspension cell line in a serum-free medium. In the present study, the growth kinetics of suspension MDCK cells and influenza virus production in the serum-...

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Bibliographic Details
Main Authors: Ding Huang, Wen-Juan Peng, Qian Ye, Xu-Ping Liu, Liang Zhao, Li Fan, Kang Xia-Hou, Han-Jing Jia, Jian Luo, Lin-Ting Zhou, Bei-Bei Li, Shi-Lei Wang, Wen-Ting Xu, Ze Chen, Wen-Song Tan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4634975?pdf=render