Expression of human hormone-sensitive lipase in white adipose tissue of transgenic mice increases lipase activity but does not enhance in vitro lipolysis

Hormone-sensitive lipase (H1111117) catalyzes the hydrolysis of acylglycerols and cholesteryl esters (CEs). The enzyme is highly expressed in adipose tissues (ATs), where it is thought to play an important role in fat mobilization. The purpose of the present work was to study the effect of a physiol...

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Bibliographic Details
Main Authors: Stéphanie Lucas, Geneviève Tavernier, Claire Tiraby, Aline Mairal, Dominique Langin
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520328315