The sodium-leak channel, NALCN, in health and disease

The sodium-leak channel, NALCN, in health and disease

Ion channels are crucial components of cellular excitability and are involved in many neurological diseases. This review focuses on the sodium leak, G protein-coupled receptors (GPCRs)-activated NALCN channel that is predominantly expressed in neurons where it regulates the resting membrane potentia...

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Bibliographic Details
Main Authors: Maud eCochet-Bissuel, Philippe eLory, Arnaud eMonteil
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
excitability
ion channel
: NALCN
UNC-79
UNC-80
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00132/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00132/full

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